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KMID : 0191120040190030453
Journal of Korean Medical Science
2004 Volume.19 No. 3 p.453 ~ p.457
Severe Chronic Active EBV Infection in an Adult Patient :Case Report
Ha SY
Chung CW/Ko YH
Abstract
Severe chronic active Epstein-Barr virus (EBV) infection is a rare and life-threatening illness. Although the criteria for diagnosis include chronic or recurrent infectious mononucleosis-like symptoms lasting more than 6 months and high titers of anti-EBV antibodies, clinical and laboratory findings may be heterogeneous and flexible application of those criteria is necessary in cases showing typical clinical and pathologic findings. We report a case of severe chronic active EBV infection in a 62-yr-old female patient who showed classical clinical findings with infiltration of EBV-infected T lymphocytes in the bone marrow, spleen, and lymph nodes, and died four months after presentation.
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